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    人 VEGFA (NM_001025366) ORF克隆产品信息

    订购信息

    货号
    种属
    载体
    描述
    价格
    周期
    YHO00237
    Human ORF
    pMD19-T Simple Vector
    Homo sapiens vascular endothelial growth factor A (VEGFA),transcript variant 1, mRNA NM_001025366
    2000
    1800
    2-3 周

    基本信息

    基因名称:
    VEGFA
    基因别名:
    MGC70609; MVCD1; VEGF; VPF
    NCBI序列号:
    NM_001025366
    基因描述:
    Homo sapiens vascular endothelial growth factor A (VEGFA),transcript variant 1, mRNA NM_001025366
    基因种属:
    Human

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    载体信息

    基因简介

    This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms.

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