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    人 PBX1 (NM_002585) 过表达慢成人伊人产品信息

    订购信息

    货号
    种属
    载体
    描述
    荧光
    价格
    周期
    LV002585
    Human
    腺成人伊人
    Homo sapiens pre-B-cell leukemia homeobox 1 (PBX1), transcript variant 1, mRNA NM_002585
    无荧光
    8500
    8000
    6-7 周

    基本信息

    基因名称:
    PBX1
    NCBI序列号:
    NM_002585
    基因描述:
    Homo sapiens pre-B-cell leukemia homeobox 1 (PBX1), transcript variant 1, mRNA NM_002585
    基因种属:
    Human
    荧光标记:
    无荧光
    慢成人伊人滴度:
    108 TU/ml

    产品说明书

    请联系YRgene技术支持索取产品说明书。

    基因简介

    This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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