- 成人伊人|伊人影院伊人影院|伊人成人综合影院|伊人综合在线影院
您好,欢迎光临赢润生物技术商城
请登录    |     免费注册     帮助中心

客服热线:0731—84317068

QQ咨询:12695920

订货邮箱:service@yrgene.com

  • 当前位置: 首页 > 启动子库

    启动子产品信息

    订购信息

    货号
    种属
    载体
    描述
    价格
    周期
    PR10340
    Human
    pDrive
    3500
    3-4 周

    产品参数

    Gene Promoter: L-Plastin (Lymphocyte cytosolic protein 1)
    Specificity: Tumor
    Backbone: pDRIVE, pDRIVE5-SEAP, pGL3-basic, pcDNA3.1-EGFP, ect.

    产品说明书

    pDRIVE-LP(human) Map 产品说明书(点击下载)

    产品说明

    Description:
    L-plastin (LP) belongs to a family of genes which encode actin-binding proteins. LP is constitutively expressed at high levels in malignant epithelial cells but is not expressed in normal tissues, except at low levels in mature hematopoietic cells. A 315-bp fragment of the 5’ region of the L-plastin gene, spanning the TATAAA box and a potential Sp1-binding site, is sufficient to exhibit strong promoter activity [1]. The L-plastin promoter driving the expression of a suicide gene was used to successfully inhibit the growth of ovarian tumor cells in vitro and in vivo [2].


    1. Lin CS. et al. 1993. Characterization of the human L-plastin gene promoter in normal and neoplastic cells. J Biol Chem 268(4):2793-801.
    2. Peng XY et al. 2001. The use of the L-plastin promoter for adenoviral-mediated, tumor-specific gene expression in ovarian and bladder cancer cell lines. Cancer Res 61(11):4405-13.

    立即购买 加入购物车

    Copyright ©2014 长沙赢润生物技术有限公司版权所有 湘ICP备15013987号-2

    技术支持