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    货号
    种属
    载体
    描述
    价格
    周期
    PR10300
    Human
    pUC57
    2200
    2-3 周

    产品参数

    Gene Promoter: Carcinoembryonic Antigen
    Specificity: Epithelial cancers
    Backbone: pDRIVE, pDRIVE5-SEAP, pGL3-basic, pUC57, pcDNA3.1-EGFP, ect.

    产品说明书

    pDRIVE-CEA(human) Map 产品说明书(点击下载)

    产品说明

    Description:
    The carcinoembryonic antigen (CEA) is a cell surface glycoprotein that is overexpressed in colorectal and other cancers of epithelial cell origin. The CEA promoter has been used to induce tumor-selective expression of exogenous genes in human colorectal [1], gastric [2] and lung cancers. In CEA producing cells, the CEA promoter has been shown to be as efficient as the SV40 enhancer/promoter in driving expression of therapeutic genes [1].


    1. Cao G. et al. 1998. Comparison of carcinoembryonic antigen promoter regions isolated from human colorectal carcinoma and normal adjacent mucosa to induce strong tumorspecific gene expression. Int J Cancer 78:242-247.
    2. Lan KH. et al. 1997. In vivo selective gene expression and therapy mediated by adenoviral vectors for human carcinoembryonic antigen-producing gastric carcinoma. Cancer Res. 57(19):4279-84.

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