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    启动子产品信息

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    货号
    种属
    载体
    描述
    价格
    周期
    PR10174
    Human
    pDrive
    3500
    3-4 周

    产品参数

    Gene Promoter: Monocyte Receptor for Bacterial LPS
    Specificity: Monocytic cells
    Backbone: pDRIVE, pDRIVE5-SEAP, pGL3-basic, pUC57, pcDNA3.1-EGFP, ect.

    产品说明书

    pDRIVE-CD14(human) Map 产品说明书(点击下载)

    pDRIVE5-SEAP-CD14(human) Map 产品说明书(点击下载)

    pDRIVE5-SEAP-CD14(human) Sequence 产品说明书(点击下载)

    产品说明

    Description:
    CD14 is a receptor for bacterial lipopolysaccharide expressed on the surface of myeloid-derived cells, and is strongly upregulated during monocytic cell differentiation. Monocyte-specific expression of CD14 is regulated at the transcriptional level. The CD14 promoter contains a C/EBP [1] and Sp1 [2] site that are critical for tissue-specific regulation of CD14 gene expression.


    1. Pan Z. et al. 1999. CCAAT/enhancer-binding protein activates the CD14 promoter and mediates transforming growth factor beta signaling in monocyte development. J Biol Chem 274(33):23242-8.
    2. Park S. et al. 2002. Synergistic interaction of MEF2D and Sp1 in activation of the CD14 promoter. Mol Immunol 39(1-2):25.

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