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    货号
    种属
    载体
    描述
    价格
    周期
    PR10156
    Human
    pDRIVE5-SEAP
    3500
    3-4 周

    产品参数

    Gene Promoter: Ubiquitin B
    Specificity: Ubiquitous
    Backbone: pDRIVE, pDRIVE5-SEAP, pGL3-basic, pcDNA3.1-EGFP, ect.

    产品说明书

    pDRIVE-Ubiquitin B(human) Map 产品说明书(点击下载)

    pDRIVE-Ubiquitin B(human) Sequence 产品说明书(点击下载)

    pDRIVE5-SEAP-Ubiquitin B(human) Map 产品说明书(点击下载)

    pDRIVE5-SEAP-Ubiquitin B(human) Sequence 产品说明书(点击下载)

    产品说明

    Description:
    Ubiquitin B (Ubi B) is a small highly conserved protein that is abundantly expressed in all eukaryotic cells. Ubi B is involved in the degradation of short-lived regulatory proteins as well as abnormal/mutated proteins and in the processing of major histocompatibility class I-restricted antigens [1]. A 1.1 kb fragment from the ubiquitin B gene was shown to display sustained expression of a transgene in vitro and in vivo. Twenty days post-injection, the levels of expression were similar to those obtained with the CMV promoter and were higher 35 days post-injection [2].


    1. Ciechanover A. and Schwartz AL. 1998. The ubiquitin-proteasome pathway: the complexity and myriad functions of proteins death. Proc Natl Acad Sci USA 95(6):2727-30.
    2. Yew NS. et al. 2001. High and sustained transgene expression in vivo from plasmid vectors containing a hybrid ubiquitin promoter. Mol Ther. 4(1):75-82.

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