- 成人伊人|伊人影院伊人影院|伊人成人综合影院|伊人综合在线影院
您好,欢迎光临赢润生物技术商城
请登录    |     免费注册     帮助中心

客服热线:0731—84317068

QQ咨询:12695920

订货邮箱:service@yrgene.com

  • 当前位置: 首页 > 启动子库

    启动子产品信息

    订购信息

    货号
    种属
    载体
    描述
    价格
    周期
    PR10056
    Human
    pcDNA3.1-EGFP
    2600
    3-4 周

    产品参数

    Gene Promoter: Ferritin Heavy Chain
    Specificity: Ubiquitous
    Backbone: pDRIVE, pDRIVE5-SEAP, pGL3-basic, pUC57, pcDNA3.1-EGFP, ect.

    产品说明书

    pDRIVE-FerH(human) Map 产品说明书(点击下载)

    产品说明

    Description:
    Ferritin is a ubiquitous iron storage protein, whose major role is to sequester and detoxify intracellular iron that has not been utilized in cellular metabolism. Ferritin is a 24 subunit protein composed of two subunit types, termed H (heavy) and L (light), which perform complementary functions in the protein. The H subunit plays a role in the rapid detoxification of iron whereas the L subunit facilitates long-term iron storage. The synthesis of ferritin is highly regulated by the iron status of the cell. The iron regulation is achieved at the translational level through interaction between a 28-nucleotide iron-responsive element (IRE), located in the 5’ untranslated region (5’UTR) of ferritin mRNAs, and a cytosolic protein, the iron regulatory protein [1]. To eliminate the iron regulation of the ferritin promoters, the 5’UTR of FerH and FerL have been replaced by the 5’UTR of the HTLV or EF-1α.


    1. Eisenstein RS & Munro HN. 1990. Translational regulation of ferritin synthesis by iron. Enzyme 44(1-4):42-58.
    2. Bevilacqua MA et al. 1992. Promoter for the human ferritin heavy chain-encoding gene (FERH): structural and functional characterization. Gene 15;111(2):255-60.

    立即购买 加入购物车

    Copyright ©2014 长沙赢润生物技术有限公司版权所有 湘ICP备15013987号-2

    技术支持